Association of DTNBP1 With Schizophrenia: Findings From Two Independent Samples of Han Chinese Population
نویسندگان
چکیده
منابع مشابه
Association study of KIBRA rs17070145 polymorphism with the risk of schizophrenia in the Han Chinese population.
Schizophrenia (SCZ) is a chronic and devastating psychiatric disorder with high heritability, which may affect approximately 1% of the world's population. To date, however, the precise pathogenesis of SCZ is still unclear. A recent genome-wide association study demonstrated that a common single nucleotide polymorphism (SNP), rs17070145, within the KIBRA gene, also known as WWC1 (WW and C2 domai...
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Both genome wide association study (GWAS) and biochemical studies of Caucasian populations indicate a robust association between the miR-137 genetic variant rs1625579 and schizophrenia, but inconsistent results have been reported. To assay the association between this variant and schizophrenia, we genotyped 611 schizophrenic patients from Southern Chinese Han population for the risk single nucl...
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AIMS Genetics play a major role in the etiology of schizophrenia (SZ). Catechol-O-methyltransferase (COMT) is one of the promising candidate genes for SZ. A nonsynonymous single-nucleotide polymorphism (SNP), rs4680, causing a Valine (Val) to Methionine (Met) substitution, has been widely studied in relation to psychiatric phenotypes, including SZ, but with conflicting results. We conducted a t...
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Schizophrenia is a chronic, severely debilitating mental disorder. Many studies have suggested that genetic factors play an important role in the onset and development of schizophrenia. In our study, we conducted a case-control study in a northern Chinese Han population of 499 schizophrenia patients and 500 controls to investigate the effect of variant genotypes of 13 SNPs in ANK3 on schizophre...
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Previous studies have found that the vaccinia related kinase 2 gene (VRK2) polymorphism was associated with schizophrenia (SCZ) in the worldwide population. This association was further supported by VRK2 mRNA expression patterns and brain structure variations. Here, we analyzed four single nucleotide polymorphisms (SNPs) of the VRK2 gene in a total population of 893 samples, consisting of 360 p...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2020
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2020.00446